a review on pharmacological, cultivation and biotechnology aspects of milk thistle (silybum marianum (l.) gaertn.)
نویسندگان
چکیده
milk thistle (silybum marianum (l.) gaertn.) is one of the valuable medicinal plants which used in the treatment of liver disorders. the major active constituents in this plant are flavonolignans, collectively known as silymarin which is a mixture of three isomer silybin, silydianin and silycristin. its therapeutic properties are due to the presence of silymarin. the seeds contain the highest amount of silymarin, but the other plant parts have less amount of this compound. the silymarin content in fruits depends on milk thistle variety and geographic and climatic condition. in this review, we summarized the accomplished investigations on aspects of medicinal, cultivation, biology and biotechnology of milk thistle.
منابع مشابه
A Review on Pharmacological, Cultivation and Biotechnology Aspects of Milk Thistle (Silybum marianum (L.) Gaertn.)
Milk thistle (Silybum marianum (L.) Gaertn.) is one of the valuable medicinal plants which used in the treatment of liver disorders. The major active constituents in this plant are flavonolignans, collectively known as silymarin which is a mixture of three isomer silybin, silydianin and silycristin. Its therapeutic properties are due to the presence of silymarin. The seeds contain the highest a...
متن کاملMilk Thistle (Silybum marianum)
Milk thistle is a well known and commonly used herb, used particularly in hepatic diseases. It has very potent antioxidant, anti-inflammatory, and antifibrotic properties (1). As a single agent its therapeutic effects in liver disease appear to be modest (2,3,4,5). Herbal medicines and supplements are likely to be much more beneficial when used synergistically in combinations or formulas. Milk ...
متن کاملPhylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle)
Use of the herb milk thistle (Silybum marianum) is widespread, and its chemistry has been studied for over 50 years. However, milk thistle endophytes have not been studied previously for their fungal and chemical diversity. We examined the fungal endophytes inhabiting this medicinal herb to determine: (1) species composition and phylogenetic diversity of fungal endophytes; (2) chemical diversit...
متن کاملCultivation of Silybum Marianum Gaertn., a Promising Medicinal Plant
Silybum marianum Gaertn., commonly known as milk thistle, seeds of which yield 'silymarine' a flavanoid, has marked antihepatotoxic properties. It is being collected in larger quantities by the pharmaceuticals. There is a great need to cultivate this plant for the sustained supply of the seeds. A package of agrotechnology of the crop is reported in this paper.
متن کاملSilybin, a Major Bioactive Component of Milk Thistle (Silybum marianum L. Gaernt.)-Chemistry, Bioavailability, and Metabolism.
Milk thistle (Silybum marianum) is a medicinal plant that has been used for thousands of years as a remedy for a variety of ailments. The main component of S. marianum fruit extract (silymarin) is a flavonolignan called silybin, which is not only the major silymarin element but is also the most active ingredient of this extract, which has been confirmed in various studies. This compound belongs...
متن کاملAntioxidant Activity of Flavolignans from Silybum marianum (L). Gaertn. Fruits
The flavolignans silybin (1) and 2,3-dehydrosilybin (2) (Figure 1) were isolated from fruits of milk thistle [Silybum marianum (L). Gaertn.] cultivated in the Samara region (Russian Federation). 2,3-dehydrosilybin (2) for the first time in Russian Federation is described for the given plant. Silybin and 2,3-dehydrosilybin and also new preparation, a fluid extract of Silybum marianum fruits, hav...
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عنوان ژورنال:
فصلنامه علمی پژوهشی گیاهان داروییجلد ۳، شماره ۴۷، صفحات ۱۹-۳۷
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